H2N2V1, Main, Exploration, bibRecord, 000D74

Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009

Identifieur interne : 000D74 ( Main/Exploration ); précédent : 000D73; suivant : 000D75

Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009

Auteurs : Andi Krumbholz [Allemagne] ; Jeannette Lange [Allemagne] ; Ralf Dürrwald [Allemagne] ; Heike Hoyer [Allemagne] ; Stefan Bengsch [Allemagne] ; Peter Wutzler [Allemagne] ; Roland Zell [Allemagne]

Source :

Journal of Medical Virology [ 0146-6615 ] ; 2010-07-15.

RBID : Hal:hal-00556041

Abstract

The Eurasian lineages of swine influenza viruses are different genetically from classical swine H1N1 influenza viruses and comprise avian-like H1N1 and human-like H1N2 and H3N2 subtypes. Although sporadic isolation of such viruses from human specimens has been reported, the prevalence of human infections is not known. In the present study, the seroprevalence against Eurasian swine influenza viruses was investigated. Sera were collected in Thuringia, Germany, from December 2007 to April 2009. The study group comprised 118 professionals with occupational exposure to pigs (50 pig slaughterers/meat inspectors, 46 pig farmers, 22 veterinarians caring for pig herds). The control group included 118 age- and gender-matched blood donors from Thuringia. As a result, 18 sera of the study group were identified with raised hemagglutination-inhibition titers against a panel of nine swine influenza viruses (three strains/subtype). For 17/18 sera this finding was confirmed in the neutralisation assay. For 11/18 sera the raise of titers was significant, i.e., a fourfold increase of hemagglutination-inhibition titers was observed. No gender-specific bias of the high titer sera was observed. Twelve sera of the control group showed increased hemagglutination-inhibition titers against swine influenza viruses. Hemagglutination-inhibition titers of 2/12 control sera were raised fourfold but did not exhibit a significant increase of neutralisation titers. All increased hemagglutination-inhibition titers of the control group may be explained by cross-reactivity with seasonal influenza virus strains, as all these sera also reacted with human strains.

Url:

https://hal.archives-ouvertes.fr/hal-00556041

DOI: 10.1002/jmv.21869

Affiliations:

Allemagne

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000244
to stream Hal, to step Curation: 000244
to stream Hal, to step Checkpoint: 000257
to stream Main, to step Merge: 000D80
to stream Main, to step Curation: 000D74

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009</title>
<author><name sortKey="Krumbholz, Andi" sort="Krumbholz, Andi" uniqKey="Krumbholz A" first="Andi" last="Krumbholz">Andi Krumbholz</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139883" status="INCOMING">          <orgName>Dept. of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Lange, Jeannette" sort="Lange, Jeannette" uniqKey="Lange J" first="Jeannette" last="Lange">Jeannette Lange</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139883" status="INCOMING">          <orgName>Dept. of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Durrwald, Ralf" sort="Durrwald, Ralf" uniqKey="Durrwald R" first="Ralf" last="Dürrwald">Ralf Dürrwald</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139884" status="INCOMING">          <orgName>Dept. Research and Development</orgName>
          <desc>            <address>              <addrLine>Dessau-Rosslau</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334432" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334432" type="direct"><org type="institution" xml:id="struct-334432" status="INCOMING">          <orgName>IDT Biologika GmbH</orgName>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Hoyer, Heike" sort="Hoyer, Heike" uniqKey="Hoyer H" first="Heike" last="Hoyer">Heike Hoyer</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139885" status="INCOMING">          <orgName>Dept. of Medical Statistics and Documentation</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Bengsch, Stefan" sort="Bengsch, Stefan" uniqKey="Bengsch S" first="Stefan" last="Bengsch">Stefan Bengsch</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139886" status="INCOMING">          <orgName>Dept. of Transfusion Medicine</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Wutzler, Peter" sort="Wutzler, Peter" uniqKey="Wutzler P" first="Peter" last="Wutzler">Peter Wutzler</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139883" status="INCOMING">          <orgName>Dept. of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Zell, Roland" sort="Zell, Roland" uniqKey="Zell R" first="Roland" last="Zell">Roland Zell</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139887" status="INCOMING">          <orgName>Institut of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>D-07745;Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-134656" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-134656" type="direct"><org type="institution" xml:id="struct-134656" status="VALID">          <orgName>Friedrich-Schiller-Universität Jena</orgName>
          <desc>            <address>              <addrLine>Fürstengraben 1 D-07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uni-jena.de/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-00556041</idno>
<idno type="halId">hal-00556041</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00556041</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-00556041</idno>
<idno type="doi">10.1002/jmv.21869</idno>
<date when="2010-07-15">2010-07-15</date>
<idno type="wicri:Area/Hal/Corpus">000244</idno>
<idno type="wicri:Area/Hal/Curation">000244</idno>
<idno type="wicri:Area/Hal/Checkpoint">000257</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000257</idno>
<idno type="wicri:doubleKey">0146-6615:2010:Krumbholz A:prevalence:of:antibodies</idno>
<idno type="wicri:Area/Main/Merge">000D80</idno>
<idno type="wicri:Area/Main/Curation">000D74</idno>
<idno type="wicri:Area/Main/Exploration">000D74</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009</title>
<author><name sortKey="Krumbholz, Andi" sort="Krumbholz, Andi" uniqKey="Krumbholz A" first="Andi" last="Krumbholz">Andi Krumbholz</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139883" status="INCOMING">          <orgName>Dept. of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Lange, Jeannette" sort="Lange, Jeannette" uniqKey="Lange J" first="Jeannette" last="Lange">Jeannette Lange</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139883" status="INCOMING">          <orgName>Dept. of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Durrwald, Ralf" sort="Durrwald, Ralf" uniqKey="Durrwald R" first="Ralf" last="Dürrwald">Ralf Dürrwald</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139884" status="INCOMING">          <orgName>Dept. Research and Development</orgName>
          <desc>            <address>              <addrLine>Dessau-Rosslau</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334432" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334432" type="direct"><org type="institution" xml:id="struct-334432" status="INCOMING">          <orgName>IDT Biologika GmbH</orgName>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Hoyer, Heike" sort="Hoyer, Heike" uniqKey="Hoyer H" first="Heike" last="Hoyer">Heike Hoyer</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139885" status="INCOMING">          <orgName>Dept. of Medical Statistics and Documentation</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Bengsch, Stefan" sort="Bengsch, Stefan" uniqKey="Bengsch S" first="Stefan" last="Bengsch">Stefan Bengsch</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139886" status="INCOMING">          <orgName>Dept. of Transfusion Medicine</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Wutzler, Peter" sort="Wutzler, Peter" uniqKey="Wutzler P" first="Peter" last="Wutzler">Peter Wutzler</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139883" status="INCOMING">          <orgName>Dept. of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-334431" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-334431" type="direct"><org type="institution" xml:id="struct-334431" status="VALID">          <orgName>Jena University Hospital [Jena]</orgName>
          <desc>            <address>              <addrLine>Bachstraße 18, 07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uniklinikum-jena.de/en/Wir_%C3%BCber_uns.html</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Zell, Roland" sort="Zell, Roland" uniqKey="Zell R" first="Roland" last="Zell">Roland Zell</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-139887" status="INCOMING">          <orgName>Institut of Virology and Antiviral Therapy</orgName>
          <desc>            <address>              <addrLine>D-07745;Jena</addrLine>
              <country key="DE"></country>
            </address>
          </desc>
          <listRelation>            <relation active="#struct-134656" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-134656" type="direct"><org type="institution" xml:id="struct-134656" status="VALID">          <orgName>Friedrich-Schiller-Universität Jena</orgName>
          <desc>            <address>              <addrLine>Fürstengraben 1 D-07743 Jena</addrLine>
              <country key="DE"></country>
            </address>
            <ref type="url">http://www.uni-jena.de/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>Allemagne</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1002/jmv.21869</idno>
<series><title level="j">Journal of Medical Virology</title>
<idno type="ISSN">0146-6615</idno>
<imprint><date type="datePub">2010-07-15</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="it"><term>Medicine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">              <p>The Eurasian lineages of swine influenza viruses are different genetically from classical swine H1N1 influenza viruses and comprise avian-like H1N1 and human-like H1N2 and H3N2 subtypes. Although sporadic isolation of such viruses from human specimens has been reported, the prevalence of human infections is not known. In the present study, the seroprevalence against Eurasian swine influenza viruses was investigated. Sera were collected in Thuringia, Germany, from December 2007 to April 2009. The study group comprised 118 professionals with occupational exposure to pigs (50 pig slaughterers/meat inspectors, 46 pig farmers, 22 veterinarians caring for pig herds). The control group included 118 age- and gender-matched blood donors from Thuringia. As a result, 18 sera of the study group were identified with raised hemagglutination-inhibition titers against a panel of nine swine influenza viruses (three strains/subtype). For 17/18 sera this finding was confirmed in the neutralisation assay. For 11/18 sera the raise of titers was significant, i.e., a fourfold increase of hemagglutination-inhibition titers was observed. No gender-specific bias of the high titer sera was observed. Twelve sera of the control group showed increased hemagglutination-inhibition titers against swine influenza viruses. Hemagglutination-inhibition titers of 2/12 control sera were raised fourfold but did not exhibit a significant increase of neutralisation titers. All increased hemagglutination-inhibition titers of the control group may be explained by cross-reactivity with seasonal influenza virus strains, as all these sera also reacted with human strains.</p>
            </div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
</list>
<tree><country name="Allemagne"><noRegion><name sortKey="Krumbholz, Andi" sort="Krumbholz, Andi" uniqKey="Krumbholz A" first="Andi" last="Krumbholz">Andi Krumbholz</name>
</noRegion>
<name sortKey="Bengsch, Stefan" sort="Bengsch, Stefan" uniqKey="Bengsch S" first="Stefan" last="Bengsch">Stefan Bengsch</name>
<name sortKey="Durrwald, Ralf" sort="Durrwald, Ralf" uniqKey="Durrwald R" first="Ralf" last="Dürrwald">Ralf Dürrwald</name>
<name sortKey="Hoyer, Heike" sort="Hoyer, Heike" uniqKey="Hoyer H" first="Heike" last="Hoyer">Heike Hoyer</name>
<name sortKey="Lange, Jeannette" sort="Lange, Jeannette" uniqKey="Lange J" first="Jeannette" last="Lange">Jeannette Lange</name>
<name sortKey="Wutzler, Peter" sort="Wutzler, Peter" uniqKey="Wutzler P" first="Peter" last="Wutzler">Peter Wutzler</name>
<name sortKey="Zell, Roland" sort="Zell, Roland" uniqKey="Zell R" first="Roland" last="Zell">Roland Zell</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D74 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000D74 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Hal:hal-00556041
   |texte=   Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021

	Serveur d'exploration H2N2
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration H2N2

Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009

Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri